Benefits of Glucosamine Chondroitin Supplements

Man Holding For Painful Knee

Glucosamine chondroitin sulfate is a popular supplement that may help in the treatment of pain that is associated with osteoarthritis. The anti-inflammatory effects of this supplement may be the key to relieving some of the pain associated with inflammation of the joints. There are other benefits of glucosamine chondroitin to consider as well.

What is Glucosamine

Glucosamine is found in cartilage that is healthy. This natural compound is found mostly in the fluid located around the joints. The glucosamine found in supplements comes from shellfish shells or is made in a laboratory.

Shellfish Shells on Pile

There are several chemical forms of glucosamine, but the one that is most often used to aid in arthritis is glucosamine sulfate. In tests conducted in a laboratory it was found that glucosamine has anti-inflammatory properties and may even help with cartilage regeneration.

What is Chondroitin

It is one of the major components of cartilage that works by helping it retain water. Chondroitin is naturally made by the body. In order to produce chondroitin supplements it is manufactured from animals such as sharks, pigs, and cows. It can also be made within a laboratory.

Chondroitin Sulfate Bottle

Chondroitin supplements are marketed as chondroitin sulfate. European countries throughout have approved chondroitin sulfate as a prescription medication that can be used in the treatment of osteoarthritis. In the United States chondroitin is typically combined with glucosamine and sold in a supplement form.

Treating Osteoarthritis With Chondroitin Sulfate

For some individuals who suffer from hand and knee osteoarthritis, chondroitin may be able to provide some additional relief from pain. The benefit is quite modest, with about an eight to ten percent improvement. It also works a bit slowly as it can take up to 3 months in order for the improvement to occur.

Osteoarthritis Knee Illustration

One study that was published in the Arthritis and Rheumatism Journal states that chondroitin sulfate can modestly improve function and relieve pain that is associated with osteoarthritis in the hand.

The supplement used in the study was made out of fish and participants took an 800 mg dose for six months. The patients reported improvements after taking the supplement for around 3 months. The participants reported having a shorter amount of time of stiffness in the mornings when taking the supplement.

There were no side effects associated with using the supplement. This makes it a good choice for those who are looking for an alternative to NSAIDS.

Treating Osteoarthritis With Glucosamine

It has been found that glucosamine can provide moderate relief from pain for patients suffering with osteoarthritis in the hip, spine, and knees. Most studies conducted about the effectiveness of glucosamine and osteoarthritis treatment found that the supplement best worked for those who suffer from osteoarthritis in the knee.

Senior Man Holding For Backs

Since glucosamine is safe to take and offers few side effects, it can be used as a replacement for NSAIDs for those that need treatment for the long term options and are unable to take NSAIDS.

Combination of Glucosamine And Chondroitin For Osteoarthritis Treatment

One of the most comprehensive studies conducted on any type of supplement was done the Glucosamine/Chondroitin Arthritis Intervention Trial or GAIT. This study looked at using the combination of glucosamine and chondroitin, each of the supplements on their own, and Celebrex and its effects on patients who suffered from osteoarthritis in the knee.

During the first part of the study it was found the combination of chondroitin and glucosamine sulfate showed a significant amount of relief from study participants who reported having moderate to severe pain in the knee.

Glucosamine Chondroitin Complex Bottle

The next part of the study looked at the prevention of joint damage of the knee. During this phase of the study it was found that a combination of glucosamine and chondroitin had little to no effect on preventing joint damage when compared to the placebo.

The differences between the placebo group and the group taking a combination of glucosamine and chondroitin, the participants that took either one of the supplements alone experienced the least amount of joint damage over a 2 year time span. This shows that it might be possible that taking both of the supplements in a combination could limit the absorption rates. This would explain the lower effects of the combination supplement’s effect.

Glucosamine Chondroitin Side Effects

If you take a glucosamine chondroitin supplement and experience any type of allergic reaction such as difficulty breathing, hives, or swelling of the lips, tongue, face, or throat, you need to seek medical attention immediately.

Woman Swollen Lip

While not all side effects of chondroitin and glucosamine are known, it is thought to be a rather safe supplement to take for up to 2 years.

Some of the common side effects of taking the supplement may include but are not limited to:

  • Hair loss
  • Puffy eyelids
  • Stomach pain, bloating, gassiness
  • Diarrhea, constipation, and nausea


Overall, chondroitin and glucosamine supplements may be effective in the treatment of osteoarthritis. The supplement has shown some improvement in symptoms in a number of patients.

Senior Couple Jumping in The Park

One of the benefits of these supplements for arthritis treatments is that unlike NSAIDs, which can be hard on the liver and other organs of the body, glucosamine and chondroitin can be safe to use over the long term.

When choosing a chondroitin glucosamine sulphate supplement it is important to consider only the best supplements available on the market. Our supplement uses only the top ingredients and will help support overall joint health and may help relieve some of the pain associated with osteoarthritis.